Journal article

Serum vitamin D levels, diabetes and cardio-metabolic risk factors in Aboriginal and Torres Strait Islander Australians

LJ Maple-Brown, JT Hughes, ZX Lu, K Jeyaraman, P Lawton, GRD Jones, A Ellis, A Sinha, A Cass, RJ Macisaac, G Jerums, K O'Dea

Diabetology and Metabolic Syndrome | BIOMED CENTRAL LTD | Published : 2014

Abstract

Background: Low levels of serum 25-hydroxy vitamin D (25(OH)D), have been associated with development of type 2 diabetes and cardiovascular disease (CVD); however there are limited data on serum 25(OH)D in Indigenous Australians, a population at high risk for both diabetes and CVD. We aimed to assess levels of serum 25(OH)D in Aboriginal and Torres Strait Islander Australians and to explore relationships between 25(OH)D and cardio-metabolic risk factors and diabetes. Methods. 592 Aboriginal and/or Torres Strait Islander Australian participants of The eGFR (estimated glomerular filtration rate) Study, a cross-sectional analysis of a cohort study performed in 2007-2011, from urban and remote c..

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University of Melbourne Researchers

Grants

Awarded by Diabetes Australia Research Trust


Funding Acknowledgements

Thanks to participants, study staff and investigators of the eGFR Study. Thanks to Roche Diagnostics for supplying the enzymatic creatinine reagent kits and Melbourne Pathology, Australia for the technical support for the analysis of enzymatic creatinine, 25(OH) D and high sensitive troponin T. The eGFR Study was funded by the National Health and Medical Research Council of Australia (NHMRC, Project Grant #545202). The views expressed are those of the authors and do not reflect the views of NHMRC. Additional support was obtained from Kidney Health Australia, NHMRC #320860, the Colonial Foundation, Diabetes Australia Research Trust, Rebecca L Cooper Foundation and SeaSwift, Thursday Island. LMB is supported by an Australian NHMRC Early Career Fellowship in Aboriginal and Torres Strait Islander Health Research (#605837). JH is supported by NHMRC Scholarship #490348, Rio Tinto Aboriginal Fund and the Centre of Clinical Research Excellence in Clinical Science of Diabetes, University of Melbourne. PL is supported by NHMRC Scholarship #1038529. Cass holds a NHMRC Principal Research Fellowship #1027204, and Hoy holds an NHMRC Australia Fellowship #511081. Funding bodies had no role in the study design, in the collection, analysis or interpretation of data, in the writing of the manuscript or the decision to submit the manuscript for publication. The authors had full access to all of the data in The eGFR Study.